Sall4 Mouse Monoclonal Antibody [A7A5]

Sall4 Mouse Monoclonal Antibody [A7A5]

• Description: Sal-like protein 4 (SALL4) is a transcription factor encoded by a member of the Spalt-like (SALL) gene family, SALL4. The SALL genes were identified based on their sequence homology to Spalt, which is a homeotic gene originally cloned in Drosophila melanogaster that is important for terminal trunk structure formation in embryogenesis and imaginal disc development in the larval stages. There are four human SALL proteins (SALL1, 2, 3, and 4) with structural homology and playing diverse roles in embryonic development, kidney function, and cancer. The SALL4 gene encodes at least three isoforms, termed A, B, and C, through alternative splicing, with the A and B forms being the most studied. SALL4 can alter gene expression changes through its interaction with many co-factors and epigenetic complexes. It is also known as a key embryonic stem cell (ESC) factor. The various SALL4-null mouse models mimic human mutations in the SALL4 gene, which were shown to cause developmental problems in patients with Okihiro/Duane-Radial-ray syndrome. These individuals frequently have family history of hand malformation and eye movement disorders.
• Product Name Alternative: AA407717 antibody AL022809 antibody AW536104 antibody C330011P20Rik antibody C78083 antibody C78563 antibody dJ1112F19.1 antibody DRRS antibody HSAL4 antibody Sal like 4 (Drosophila) antibody Sal like 4 antibody Sal like Protein 4 antibody Sal-like protein 4 antibody Sall4 antibody SALL4_HUMAN antibody Spalt like transcription factor 4 antibody Tex20 antibody Zinc finger protein 797 antibody Zinc finger protein SALL4 antibody ZNF797 antibody
• Abbreviation: SALL4
• CAS Number: 9007-83-4
• Swiss Prot: Q9UJQ4 Human
• Cellular Locus: Cytoplasm, Nucleus.
• Host: Mouse
• Species Reactivity: Human
• Immunogen: Recombinant protein within human Sall4 aa 903-1,053/1,053
• Isotype: IgG1
• Conjugation: Non-conjugated
• Type: Mouse monoclonal Antibody
• Applications: WB, IHC-P
• Positive Control: NCCIT cell lysates, human seminoma tissue.
• Concentration: 2 mg/mL
• Dilution: WB: 1:2,000 ;IHC-P: 1:600
• Purity: Protein G affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 112 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: No