CD151 Mouse Monoclonal Antibody [A6G11]

• Description:

  CD151 molecule (Raph blood group), also known as CD151 (Cluster of Differentiation 151), is a human gene. The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene. Abnormalities in CD151 have been implicated in a form of epidermolysis bullosa.

• Product Name Alternative:

  CD151 antibody CD151 antigen antibody CD151 molecule (Raph blood group) antibody CD151 molecule antibody CD151_HUMAN antibody GP27 antibody hemidesmosomal tetraspanin CD151 antibody Membrane glycoprotein SFA-1 antibody MER2 antibody PETA-3 antibody PETA3 antibody Platelet endothelial tetraspan antigen 3 antibody platelet surface glycoprotein gp27 antibody Platelet-endothelial cell tetraspan antigen 3 antibody Platelet-endothelial tetraspan antigen 3 antibody RAPH antibody Red blood cell antigen MER2 antibody SFA 1 antibody SFA1 antibody Tetraspanin-24 antibody Tspan-24 antibody TSPAN24 antibody

• Abbreviation:

  CD151

• Swiss Prot:

  P48509 Human, O35566 Mouse

• Cellular Locus:

  Membrane.

• Host:

  Mouse

• Species Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant protein within human CD151 aa 104-253.

• Isotype:

  IgG1

• Conjugation:

  Non-conjugated

• Type:

  Mouse monoclonal Antibody

• Applications:

  WB, IF-Cell, IHC-P

• Positive Control:

  Daudi cell lysate, HepG2 cell lysate, A431, A549, human kidney tissue, mouse liver tissue.

• Concentration:

  2 mg/mL

• Dilution:

  WB: 1:1,000 ;IF-Cell: 1:100 ;IHC-P: 1:500

• Purity:

  Protein A affinity purified.

• Form:

  Liquid

• Buffer:

  PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size: 28 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  No

• CAS Number:

  9007-83-4