IL-6R Rabbit Polyclonal Antibody

• Description:

  This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.

• Product Name Alternative:

  CD 126 antibody CD126 antibody CD126 antigen antibody gp80 antibody IL 6R 1 antibody IL 6R alpha antibody IL 6R antibody IL-6 receptor alpha chain antibody IL-6 receptor subunit alpha antibody IL-6R 1 antibody IL-6R subunit alpha antibody IL-6R-alpha antibody IL-6RA antibody IL6Q antibody Il6r antibody IL6RA antibody IL6RA_HUMAN antibody IL6RQ antibody Interleukin 6 receptor antibody interleukin 6 receptor, alpha antibody Interleukin-6 receptor subunit alpha antibody Membrane glycoprotein 80 antibody MGC30256 antibody

• Abbreviation:

  IL6R

• Swiss Prot:

  P08887 Human

• Cellular Locus:

  Cell membrane, Secreted.

• Host:

  Rabbit

• Species Reactivity:

  Human

• Immunogen:

  Synthetic peptide within human IL-6R aa 20-69/468.

• Isotype:

  IgG

• Conjugation:

  Non-conjugated

• Type:

  Rabbit polyclonal Antibody

• Applications:

  WB, IF-Cell, IHC-P

• Positive Control:

  Daudi cell lysate, A549 cell lysate, K562 cell lysate, Hela, human fetal skeletal muscle tissue.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:1,000;IF-Cell: 1:200;IHC-P: 1:600

• Purity:

  Immunogen affinity purified.

• Form:

  Liquid

• Buffer:

  PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size: 52 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  No

• CAS Number:

  9007-83-4