Urokinase Rabbit Polyclonal Antibody
CAT:
992-HA500429
Size:
100 µL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Urokinase Rabbit Polyclonal Antibody
- Description: Urokinase, also known as urokinase-type plasminogen activator (uPA), is a serine protease present in humans and other animals. The human urokinase protein was discovered, but not named, by McFarlane and Pilling in 1947. Urokinase was originally isolated from human urine, and it is also present in the blood and in the extracellular matrix of many tissues. The primary physiological substrate of this enzyme is plasminogen, which is an inactive form (zymogen) of the serine protease plasmin. Activation of plasmin triggers a proteolytic cascade that, depending on the physiological environment, participates in thrombolysis or extracellular matrix degradation. This cascade had been involved in vascular diseases and cancer progression. Urokinase is encoded in humans by the PLAU gene, which stands for "plasminogen activator, urokinase". The same symbol represents the gene in other animal species.
- Product Name Alternative: ATF antibody ATF uPA antibody BDPLT5 antibody Plasminogen activator antibody Plasminogen activator urinary antibody Plasminogen activator urokinase antibody PLAU antibody QPD antibody u PA antibody U plasminogen activator antibody u-PA antibody U-plasminogen activator antibody uPA antibody URK antibody UROK_HUMAN antibody Urokinase plasminogen activator antibody Urokinase type plasminogen activator antibody Urokinase type plasminogen activator precursor antibody Urokinase-type plasminogen activator chain B antibody hide
- Abbreviation: Anti-Urokinase antibody
- CAS Number: 9007-83-4
- Swiss Prot: P00749 Human, P29598 Rat
- Cellular Locus: Secreted.
- Host: Rabbit
- Species Reactivity: Human, Rat
- Immunogen: Recombinant protein within Human Urokinase 10- 200 aa
- Isotype: IgG
- Conjugation: Non-conjugated
- Type: Rabbit polyclonal Antibody
- Applications: WB, IF-Cell
- Positive Control: PC-3M cell lysate, MCF-7 cell lysate, LANCAP cell lysate, rat kidney tissue lysate, rat stomach tissue lysate, PC-3M.
- Concentration: 1 mg/mL
- Dilution: WB: 1,000-2,000;IF-Cell: 1:200
- Purity: Immunogen affinity purified.
- Form: Liquid
- Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
- Molecular Weight: Predicted band size: 49 kDa
- Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
- Recombinant Antibody: No