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Urokinase Rabbit Polyclonal Antibody

CAT: 0992-HA500429Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-HA500429Size:100 µL
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Description
Urokinase, also known as urokinase-type plasminogen activator (uPA), is a serine protease present in humans and other animals. The human urokinase protein was discovered, but not named, by McFarlane and Pilling in 1947. Urokinase was originally isolated from human urine, and it is also present in the blood and in the extracellular matrix of many tissues. The primary physiological substrate of this enzyme is plasminogen, which is an inactive form (zymogen) of the serine protease plasmin. Activation of plasmin triggers a proteolytic cascade that, depending on the physiological environment, participates in thrombolysis or extracellular matrix degradation. This cascade had been involved in vascular diseases and cancer progression. Urokinase is encoded in humans by the PLAU gene, which stands for "plasminogen activator, urokinase". The same symbol represents the gene in other animal species.
CAS Number
9007-83-4
Product Name Alternative
ATF antibody ATF uPA antibody BDPLT5 antibody Plasminogen activator antibody Plasminogen activator urinary antibody Plasminogen activator urokinase antibody PLAU antibody QPD antibody u PA antibody U plasminogen activator antibody u-PA antibody U-plasminogen activator antibody uPA antibody URK antibody UROK_HUMAN antibody Urokinase plasminogen activator antibody Urokinase type plasminogen activator antibody Urokinase type plasminogen activator precursor antibody Urokinase-type plasminogen activator chain B antibody hide
Abbreviation
Anti-Urokinase antibody
Swiss Prot
P00749 Human, P29598 Rat
Cellular Locus
Secreted.
Host
Rabbit
Species Reactivity
Human, Rat
Immunogen
Recombinant protein within Human Urokinase 10- 200 aa
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell
Positive Control
PC-3M cell lysate, MCF-7 cell lysate, LANCAP cell lysate, rat kidney tissue lysate, rat stomach tissue lysate, PC-3M.
Concentration
1 mg/mL
Dilution
WB: 1,000-2,000;IF-Cell: 1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 49 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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