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PSMD7 Rabbit Polyclonal Antibody

CAT: 0992-HA500354Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-HA500354Size:100 µL
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Description
26S proteasome non-ATPase regulatory subunit 7, also known as 26S proteasome non-ATPase subunit Rpn8, is an enzyme that in humans is encoded by the PSMD7 gene. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.
CAS Number
9007-83-4
Product Name Alternative
26S proteasome non ATPase regulatory subunit 7 antibody 26S proteasome non-ATPase regulatory subunit 7 antibody 26S proteasome regulatory subunit RPN8 antibody 26S proteasome regulatory subunit S12 antibody integration site gene, mouse, homolog of antibody Moloney leukemia virus 34 proviral antibody Moloney leukemia virus 34 proviral integration antibody MOV34 antibody Mov34 homolog antibody Mov34 protein homolog antibody MOV34L antibody P40 antibody Proteasome (prosome, macropain) 26S subunit, non ATPase 7 antibody Proteasome (prosome, macropain) 26S subunit, non ATPase, 7 (Mov34 homolog) antibody Proteasome 26S S12 antibody Proteasome 26S subunit, no-ATPase, 7 antibody Proteasome subunit p40 antibody PSD7_HUMAN antibody PSMD 7 antibody PSMD7 antibody Rpn8 antibody S12 antibody
Abbreviation
PSMD7
Swiss Prot
P51665 Human, P26516 Mouse,
Cellular Locus
Cytosol, extracellular exosome, extracellular region, nucleoplasm, nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human PSMD7 aa 1-200 / 324.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
K562 cell lysate, mouse testis tissue lysate, Hela cell lysate, rat testis tissue lysate, rat brain tissue, human colon tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000 ;IHC-P: 1:200-1:600
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 37 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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