HLA E Rabbit Polyclonal Antibody

• Description:

  HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.

• Product Name Alternative:

  HLA class I histocompatibility antigen E alpha chain antibody EA1.2 antibody EA2.1 antibody HLA 6.2 antibody HLA class I histocompatibility antigen alpha chain E antibody HLA class I histocompatibility antigen E alpha chain precursor antibody HLA class I histocompatibility antigen E alpha chain precursor antibody HLA6.2 antibody HLAE antibody Lymphocyte antigen antibody Major histocompatibility complex class I E antibody MHC antibody MHC class I antigen E antibody MHC HLA E alpha 1 antibody MHC HLA E alpha 2.1 antibody QA1 antibody

• Abbreviation:

  HLA-E

• Swiss Prot:

  P13747 Human

• Cellular Locus:

  Golgi apparatus membrane, Cell membrane, Secreted.

• Host:

  Rabbit

• Species Reactivity:

  Human

• Immunogen:

  Recombinant protein within human HLA E aa 22-200 / 358 (Extracellular).

• Isotype:

  IgG

• Conjugation:

  Non-conjugated

• Type:

  Rabbit polyclonal Antibody

• Applications:

  WB, FC

• Positive Control:

  Raji cell lysate, THP-1 cell lysate, HL-60 cell lysate, SiHa.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:500-1:2,000 ;FC: 1:100-1:500

• Purity:

  Immunogen affinity purified.

• Form:

  Liquid

• Buffer:

  1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  40 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  No

• CAS Number:

  9007-83-4