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FARS2 Rabbit Polyclonal Antibody

CAT: 0992-HA500261Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-HA500261Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This gene encodes a protein that transfers phenylalanine to its cognate tRNA. This protein localizes to the mitochondrion and plays a role in mitochondrial protein translation. Mutations in this gene can cause combined oxidative phosphorylation deficiency 14 (Alpers encephalopathy). Alternative splicing results in multiple transcript variants. Is responsible for the charging of tRNA (Phe) with phenylalanine in mitochondrial translation. To a lesser extent, also catalyzes direct attachment of m-Tyr (an oxidized version of Phe) to tRNA (Phe), thereby opening the way for delivery of the misacylated tRNA to the ribosome and incorporation of ROS-damaged amino acid into proteins.
CAS Number
9007-83-4
Product Name Alternative
dJ236A3.1 (phenylalanine tRNA synthetase) antibody dJ520B18.2 (FARS1 (phenylalanine tRNA synthetase)) antibody FARS1 antibody Fars2 antibody HSPC320 antibody Phenylalanine translase antibody Phenylalanine tRNA ligase 2, mitochondrial antibody Phenylalanine tRNA ligase antibody Phenylalanine tRNA synthetase 1 (mitochondrial) antibody Phenylalanine tRNA synthetase 2 (mitochondrial) antibody Phenylalanine--tRNA ligase antibody Phenylalanyl tRNA synthetase 2 antibody Phenylalanyl-tRNA synthetase, mitochondrial antibody PheRS antibody SYFM_HUMAN antibody
Abbreviation
FARS2
Swiss Prot
O95363 Human, Q99M01 Mouse, Q6AYQ3 Rat
Cellular Locus
Mitochondrion matrix, Mitochondrion.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within human FARS2 aa 50-100 / 451.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
Rat colon tissue lysate, 293T cell lysate, SH-SY5Y, rat testis tissue, human small intestine tissue, mouse cerebellum tissue, SiHa.
Concentration
1 mg/mL
Dilution
WB: 1:1,000;IF-Cell: 1:50;IHC-P: 1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 52 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

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