Nucleoside Phosphorylase Rabbit Polyclonal Antibody

Nucleoside Phosphorylase Rabbit Polyclonal Antibody

• Description: Purine nucleoside phosphorylase is an enzyme involved in purine metabolism. PNP metabolizes inosine into hypoxanthine and guanosine into guanine, in each case creating ribose phosphate. Note: adenosine is first metabolized to inosine via the enzyme adenosine deaminase.One of the reaction catalyzed by purine nucleoside phosphorylase in purine metabolism.Nucleoside phosphorylase is an enzyme which cleaves a nucleoside by phosphorylating the ribose to produce a nucleobase and ribose 1 phosphate. It is one enzyme of the nucleotide salvage pathways. These pathways allow the cell to produce nucleotide monophosphates when the de novo synthesis pathway has been interrupted or is non-existent (as is the case in the brain). Often the de novo pathway is interrupted as a result of chemotherapy drugs such as methotrexate or aminopterin.All salvage pathway enzymes require a high energy phosphate donor such as ATP or PRPP.
• Product Name Alternative: FLJ94043 antibody FLJ97288 antibody FLJ97312 antibody Inosine phosphorylase antibody Inosine-guanosine phosphorylase antibody MGC117396 antibody MGC125915 antibody MGC125916 antibody NP antibody Np1 antibody Nucleoside phosphorylase antibody PNP antibody Pnp1 antibody PNPH_HUMAN antibody PRO1837 antibody PUNP antibody Purine nucleoside orthophosphate ribosyltransferase antibody Purine nucleoside phosphorylase 5a antibody Purine nucleoside phosphorylase antibody
• Abbreviation: Purine nucleoside phosphorylase PNP Inosine phosphorylase Inosine-guanosine phosphorylase
• CAS Number: 9007-83-4
• Swiss Prot: P00491 Human, P85973 Rat
• Cellular Locus: Cytoplasm, Cytoskeleton.
• Host: Rabbit
• Species Reactivity: Human, Rat
• Immunogen: Recombinant protein within human Nucleoside Phosphorylase aa 1-200.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: WB, IF-Cell, IHC-P, FC
• Positive Control: Rat spleenl tissue lysate, Jurkat cell lysate, K562 cell lysate, human placenta tissue, human small intestine tissue, SiHa.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500-1:1,000;IF-Cell: 1:50-1:200;IHC-P: 1:200-1:1,000;FC: 1:500-1:1,000
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: 32 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: No