Nucleoside Phosphorylase Rabbit Polyclonal Antibody

• Description:

  Purine nucleoside phosphorylase is an enzyme involved in purine metabolism. PNP metabolizes inosine into hypoxanthine and guanosine into guanine, in each case creating ribose phosphate. Note: adenosine is first metabolized to inosine via the enzyme adenosine deaminase.One of the reaction catalyzed by purine nucleoside phosphorylase in purine metabolism.Nucleoside phosphorylase is an enzyme which cleaves a nucleoside by phosphorylating the ribose to produce a nucleobase and ribose 1 phosphate. It is one enzyme of the nucleotide salvage pathways. These pathways allow the cell to produce nucleotide monophosphates when the de novo synthesis pathway has been interrupted or is non-existent (as is the case in the brain). Often the de novo pathway is interrupted as a result of chemotherapy drugs such as methotrexate or aminopterin.All salvage pathway enzymes require a high energy phosphate donor such as ATP or PRPP.

• Product Name Alternative:

  FLJ94043 antibody FLJ97288 antibody FLJ97312 antibody Inosine phosphorylase antibody Inosine-guanosine phosphorylase antibody MGC117396 antibody MGC125915 antibody MGC125916 antibody NP antibody Np1 antibody Nucleoside phosphorylase antibody PNP antibody Pnp1 antibody PNPH_HUMAN antibody PRO1837 antibody PUNP antibody Purine nucleoside orthophosphate ribosyltransferase antibody Purine nucleoside phosphorylase 5a antibody Purine nucleoside phosphorylase antibody

• Abbreviation:

  Purine nucleoside phosphorylase PNP Inosine phosphorylase Inosine-guanosine phosphorylase

• Swiss Prot:

  P00491 Human, P85973 Rat

• Cellular Locus:

  Cytoplasm, Cytoskeleton.

• Host:

  Rabbit

• Species Reactivity:

  Human, Rat

• Immunogen:

  Recombinant protein within human Nucleoside Phosphorylase aa 1-200.

• Isotype:

  IgG

• Conjugation:

  Non-conjugated

• Type:

  Rabbit polyclonal Antibody

• Applications:

  WB, IF-Cell, IHC-P, FC

• Positive Control:

  Rat spleenl tissue lysate, Jurkat cell lysate, K562 cell lysate, human placenta tissue, human small intestine tissue, SiHa.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:500-1:1,000;IF-Cell: 1:50-1:200;IHC-P: 1:200-1:1,000;FC: 1:500-1:1,000

• Purity:

  Immunogen affinity purified.

• Form:

  Liquid

• Buffer:

  1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  32 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  No

• CAS Number:

  9007-83-4