Thymidine Phosphorylase Recombinant Mouse Monoclonal Antibody [A1A10-R]

Thymidine Phosphorylase Recombinant Mouse Monoclonal Antibody [A1A10-R]

• Description: Platelet-derived endothelial cell growth factor (PD-ECGF), which is alternatively designated thymidine phosphorylase or gliostatin, is an angiogenic inducer that potently stimulates the growth of endothelial cells and induces chemotaxis. Biologically active PD-ECGF is a functional dimer that consists of two single polypeptide chains that are expressed in platelets, placenta, foreskin fibroblasts and various squamous cell carcinomas, and they are slowly secreted from the cells. In addition, PD-ECGF is overexpressed in tumor and lesional psoriatic skin and lesional epidermis, indicating that it may play a role in the pathophysiology of psoriasis. Serine residues of PD-ECGF are frequently associated with nucleotide triphosphates, including ATP. In an ATP dependent manner, PD-ECGF is also able to catalyze the reversible phosphorolysis of thymidine to thymine, as it contains thymidine phosphorylase activities.
• Product Name Alternative: ECGF 1 antibody ECGF antibody ECGF1 antibody Endothelial cell growth factor 1 antibody Endothelial cell growth factor 1 platelet derived antibody Endothelial cell growth factor, platelet-derived antibody Gliostatin antibody hPD ECGF antibody MEDPS1 antibody MNGIE antibody MTDPS1 antibody PD ECGF antibody PD-ECGF antibody PDECGF antibody PDEGF antibody Platelet derived endothelial cell growth factor antibody Platelet derived endothelial growth factor antibody Platelet-derived endothelial cell growth factor antibody TdRPase antibody Thymidine phosphorylase antibody TP antibody Tymp antibody TYPH_HUMAN antibody
• Abbreviation: Thymidine phosphorylase TP Gliostatin Platelet-derived endothelial cell growth factor PD-ECGF TdRPase TYMP
• CAS Number: 9000-83-3
• Swiss Prot: P19971 Human, Q99N42 Mouse, Q5FVR2 Rat
• Cellular Locus: Cytosol.
• Host: Mouse
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Recombinant protein within Human Thymidine Phosphorylase aa 19-239 / 482.
• Isotype: IgG1
• Clone: A1A10-R
• Conjugation: Non-conjugated
• Type: Recombinant Mouse monoclonal Antibody
• Applications: WB, IHC-P
• Positive Control: THP-1 cell lysate, A549 cell lysate, A431 cell lysate, HeLa cell lysate, mouse spleen tissue, rat spleen tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000 ;IHC-P: 1:3,000-1:10,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 50 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes