Alcohol Dehydrogenase Recombinant Rabbit Monoclonal Antibody [JG82-31]

Alcohol Dehydrogenase Recombinant Rabbit Monoclonal Antibody [JG82-31]

• Description: The alcohol dehydrogenase family of proteins metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class I alcohol dehydrogenase, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha (ADH1A), beta (ADH1B) and gamma (ADH1C) subunits are tandemly organized on chromosome 4q22 as a gene cluster. The alpha form of ADH is monomorphic and predominant in fetal and infant livers, becoming less active in gestation and only weakly active during adulthood. The genes encoding beta and gamma subunits, however, are polymorphic and strongly expressed in adult livers. With the coenzyme NAD, ADH catalyzes the reversible conversion of organic alcohols to ketones or aldehydes. The physiologic function for ADH in the liver is the removal of ethanol formed by microorganisms in the intestinal tract.
• Product Name Alternative: ADH alpha subunit antibody ADH antibody ADH1 antibody ADH1A antibody ADH1A_HUMAN antibody Alcohol dehydrogenase 1 (class I), alpha polypeptide antibody Alcohol dehydrogenase 1 antibody Alcohol dehydrogenase 1A (class I), alpha polypeptide antibody Alcohol dehydrogenase 1A antibody Alcohol dehydrogenase subunit alpha antibody Aldehyde reductase antibody
• Abbreviation: ADH1A, ADH1
• CAS Number: 9000-83-3
• Swiss Prot: P07327 Human, P00329 Mouse, P06757 Rat
• Cellular Locus: Cytoplasm.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Recombinant protein within Human Alcohol Dehydrogenase aa 2-107 / 375.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IHC-P, IF-Cell, IF-Tissue
• Positive Control: Rat liver tissue lysates, HepG2, human liver tissue, mouse liver tissue, rat liver tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500-1:2,000;IF-Cell: 1:50-1:100;IHC-P: 1:50-1:200
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: 40 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes