MAPKAP Kinase 2 Recombinant Rabbit Monoclonal Antibody [JU30-31]

• Description:

  The MAPKAP kinases (for MAP kinase activated protein kinases) are a group of MAP kinase substrates which are themselves kinases. In response to activation, the MAP kinases phosphorylate downstream components on a consensus Pro-X-Ser/Thr-Pro motif. Several kinases that contain this motif have been identifed and serve as substrates for the ERK and p38 MAP kinases. These include the serine/threonine kinases Rsk-1 (also designated MAPKAP kinase-1), Rsk-2 and Rsk-3, which are phosphorylated by ERK1 and ERK2. Similarly, p38 phosphorylates and activates the serine/threonine kinases MAPKAP kinase-2 and MAPKAP kinase-3 (also designated 3pK). The serine/threonine kinases Mnk1 and Mnk2 are substrates for both ERK and p38 MAP kinases.

• Product Name Alternative:

  MAP kinase activated protein Kinase 2 antibody MAP kinase-activated protein kinase 2 antibody MAPK activated protein kinase 2 antibody MAPK-activated protein kinase 2 antibody MAPK2_HUMAN antibody MAPKAP K2 antibody MAPKAP kinase 2 antibody MAPKAPK 2 antibody MAPKAPK-2 antibody MAPKAPK2 antibody Mitogen activated protein kinase activated protein kinase 2 antibody MK 2 antibody MK2 antibody

• Abbreviation:

  MAPK-activated protein kinase 2, MAPKAP kinase 2, MAPKAP-K2, MAPKAPK-2, MK-2, MK2, MAPKAPK2

• Swiss Prot:

  P49137 Human, P49138 Mouse

• Cellular Locus:

  Cytoplasm. Nucleus.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse

• Immunogen:

  Synthetic peptide within Human MAPKAP Kinase 2 aa 351-400 / 400.

• Isotype:

  IgG

• Conjugation:

  Non-conjugated

• Type:

  Recombinant Rabbit monoclonal Antibody

• Applications:

  WB, IP

• Positive Control:

  SK-Br-3 cell lysates.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:500-1:1,000 ;IP: 1:10-1:50

• Purity:

  Protein A affinity purified.

• Form:

  Liquid

• Buffer:

  1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size: 46 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

• Recombinant Antibody:

  Yes

• CAS Number:

  9000-83-3