Plexin A1 Recombinant Rabbit Monoclonal Antibody [JU50-37]

• Description:

  Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.

• Product Name Alternative:

  NOV antibody NOV/plexin A1 protein antibody NOVP antibody Plexin-A1 antibody Plexin1 antibody PlexinA1 antibody PLXA1_HUMAN antibody PLXN1 antibody Plxna1 antibody PLXNA1 protein antibody Semaphorin receptor NOV antibody

• Abbreviation:

  PLXNA1, NOV, PLXN1

• CAS Number:

  9000-83-3

• Swiss Prot:

  Q9UIW2 Human, P70206 Mouse, D3Z981 Rat

• Cellular Locus:

  Cell membrane.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein within Human Plexin A1 aa 100-200 / 1,896.

• Isotype:

  IgG

• Conjugation:

  Non-conjugated

• Type:

  Recombinant Rabbit monoclonal Antibody

• Applications:

  WB, IF-Cell, FC

• Positive Control:

  K-562 cell lysate, HUVEC cell lysate, mouse brain tissue lysate, rat brain tissue lysate, LOVO.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:1,000 ;IF-Cell: 1:50-1:200 ;FC: 1:50-1:100

• Purity:

  Protein A affinity purified.

• Form:

  Liquid

• Buffer:

  1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size: 211 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

• Recombinant Antibody:

  Yes