Dynamin 2 Recombinant Rabbit Monoclonal Antibody [JM61-38]

Dynamin 2 Recombinant Rabbit Monoclonal Antibody [JM61-38]

• Description: Dynamin-2 is a protein that in humans is encoded by the DNM2 gene. Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Four alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined.
• Product Name Alternative: CMT2M antibody CMTDI1 antibody CMTDIB antibody DI CMTB antibody Dnm2 antibody DYN II antibody DYN2 antibody DYN2_HUMAN antibody Dynamin II antibody Dynamin-2 antibody Dynamin2 antibody DynaminII antibody DYNII antibody
• Abbreviation: DNM2, DYN2
• CAS Number: 9000-83-3
• Swiss Prot: P50570 Human, P39054 Mouse, P39052 Rat
• Cellular Locus: Cytoplasm.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within Human Dynamin 2 aa 748-797 / 870.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, IF-Tissue, IHC-P, FC
• Positive Control: HeLa cell lysate, Jurkat cell lysate, HepG2 cell lysate, SK-OV-3 cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, mouse brain tissue lysate, rat brain tissue lysate, 293T, Hela, human kidney tissue, human fetal skeletal muscle tissue, mouse testis tissue, mouse colon tissue, mouse fallopian tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000 ;IF-Cell: 1:100-1:500 ;IF-Tissue: 1:100-1:500 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 98 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes