TXNRD1 Recombinant Rabbit Monoclonal Antibody [JA11-32]

TXNRD1 Recombinant Rabbit Monoclonal Antibody [JA11-32]

• Description: Thioredoxin (Trx) is a redox protein that is found in several species, such as bacteria, plants and mammals, and contains a conserved active site, consisting of Trp-Cys-Gly-Pro-Cys. Trx reductases (TrxR1 and TrxR2) are ubiquitous Ly noble flavoproteins that catalyze the NADPH-dependent reduction of Trx as well as several other oxidized cellular components. Mammalian Trx reductases are a part of a selenium-containing pyridine nucleotide-disulphide oxidoreductase family, which has a conserved catalytic site of Cys-Val- Asn-Val-Gly-Cys. TrxR1 and TrxR2 are also involved in the prevention of oxidative stress. Inhibition of TrxR activity may provide for potential treatments of cancer, AIDS and other autoimmune diseases as well as bacterial infections and parasitic diseases.
• Product Name Alternative: cytoplasmic antibody Gene associated with retinoic and IFN-induced mortality 12 protein antibody Gene associated with retinoic and interferon-induced mortality 12 protein antibody Gene associated with retinoid IFN induced mortality 12 protein antibody GRIM 12 antibody GRIM-12 antibody GRIM12 antibody KDRF antibody KM 102 derived reductase like factor antibody KM-102-derived reductase-like factor antibody MGC9145 antibody Oxidoreductase antibody Thioredoxin reductase 1 antibody Thioredoxin reductase 1 cytoplasmic antibody Thioredoxin reductase GRIM 12 antibody Thioredoxin reductase TR1 antibody TR 1 antibody TR antibody TR1 antibody TRXR 1 antibody TRXR1 antibody TRXR1_HUMAN antibody TXNR antibody TXNRD 1 antibody Txnrd1 antibody
• Abbreviation: TR, GRIM-12, TXNRD1, GRIM12, KDRF
• CAS Number: 9000-83-3
• Swiss Prot: Q16881 Human, Q9JMH6 Mouse, O89049 Rat
• Cellular Locus: Cytoplasm. Nucleus.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Recombinant protein with Human TXNRD1 aa 1-649 / 649.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IF-Cell, IHC-P, IP, FC
• Positive Control: Hela cell lysate, human liver tissue lysate, HUVEC, human kidney tissue, mouse testis tissue, SH-SY5Y.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500-1:2,000;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:100
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: 55 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes