MEF2A Recombinant Rabbit Monoclonal Antibody [JA33-04]

• Description:

  Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT]4TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter.

• Product Name Alternative:

  ADCAD1 antibody MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A) antibody MEF2 antibody MEF2A antibody MEF2A_HUMAN antibody Myocyte enhancer factor 2A antibody Myocyte-specific enhancer factor 2A antibody RSRFC4 antibody RSRFC9 antibody Serum response factor like protein 1 antibody Serum response factor-like protein 1 antibody

• Abbreviation:

  MEF2A, MEF2

• Swiss Prot:

  Q02078 Human, Q60929 Mouse, Q2MJT0 Rat

• Cellular Locus:

  Nucleus.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein with Human MEF2A aa 415-507 / 507.

• Isotype:

  IgG

• Conjugation:

  Non-conjugated

• Type:

  Recombinant Rabbit monoclonal Antibody

• Applications:

  WB, IHC-P

• Positive Control:

  Daudi cell lysates, human tonsil tissue, human lymph nodes tissue, human colon tissue, mouse brain tissue, mouse spleen tissue, mouse hippocampus tissue.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:500 ;IHC-P: 1:200-1:500

• Purity:

  Protein A affinity purified.

• Form:

  Liquid

• Buffer:

  1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size: 55 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

• Recombinant Antibody:

  Yes

• CAS Number:

  9000-83-3