Leptin Receptor Recombinant Rabbit Monoclonal Antibody [JA73-01]

• Description:

  Receptor for obesity factor (leptin). On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway.

• Product Name Alternative:

  CD 295 antibody CD295 antibody CD295 antigen antibody Db antibody Fa antibody HuB219 antibody LEP R antibody LEP-R antibody LEPR antibody LEPR_HUMAN antibody LEPRD antibody Leptin receptor antibody Leptin receptor fatty antibody Leptin receptor gene related protein antibody Leptin receptor precursor antibody Leptin receptor precursor antibody OB R gene related protein antibody OB receptor antibody OB-R antibody OB-RGRP antibody obl antibody Obr antibody

• Abbreviation:

  LEP-R, OB-R, LEPR, DB, OBR

• Swiss Prot:

  P48357 Human, P48356 Mouse, Q62959 Rat

• Cellular Locus:

  Cell membrane, Basolateral cell membrane.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic peptide within Human Leptin Receptor aa 1041-1090 / 1165.

• Isotype:

  IgG

• Conjugation:

  Non-conjugated

• Type:

  Recombinant Rabbit monoclonal Antibody

• Applications:

  WB, IF-Cell, IHC-P, FC

• Positive Control:

  Mouse lung tissue lysate, mouse liver tissue lysate, K-562 cell lysates, HeLa cell lysates, rat brain tissue lysates, MCF-7, rat heart tissue, human liver carcinoma tissue, human prostate tissue, human kidney tissue, mouse small intestine tissue, K562.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:500-1:2,000 ;IF-Cell: 1:50-1:100 ;IHC-P: 1:50-1:1,000 ;FC: 1:50-1:100

• Purity:

  Protein A affinity purified.

• Form:

  Liquid

• Buffer:

  1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size: 132 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

• Recombinant Antibody:

  Yes

• CAS Number:

  9000-83-3