alpha sarcoglycan Recombinant Rabbit Monoclonal Antibody [JA51-81]

alpha sarcoglycan Recombinant Rabbit Monoclonal Antibody [JA51-81]

• Description: The sarcoglycan transmembrane proteins are members of the dystrophin complex. Sarcoglycans cluster together to form a complex, which is localized in the cell membrane of skeletal, cardiac, and smooth muscle fibers. Four sarcoglycan subunit proteins, designated α-, β-, γ- and δ-sarcoglycan, form a complex on the skeletal muscle cell surface membrane. A genetic defect in any one of these proteins causes the loss or marked decrease of the whole sarcoglycan complex, which is observed in the autosomal recessive muscular dystrophy, sarcoglycanopathy. In smooth muscle, β- and δ-sarcoglycans are associated with ε-sarcoglycan, a glycoprotein homologous to α-sarcoglycan. Additionally, a complete deficiency in δ-sarcoglycan is the cause of the Syrian hamster BIO.14 cardiomyopathy.
• Product Name Alternative: 50 DAG antibody 50 kDa dystrophin associated glycoprotein antibody 50 kDa dystrophin-associated glycoprotein antibody 50DAG antibody 50kD DAG antibody 59kDa antibody A2 antibody adhalin antibody ADL antibody Alpha SG antibody Alpha-sarcoglycan antibody Alpha-SG antibody Asg antibody DAG2 antibody DMDA2 antibody Dystroglycan 2 antibody Dystroglycan-2 antibody LGMD2D antibody sarcoglycan, alpha (dystrophin-associated glycoprotein) antibody SCARMD1 antibody Sgca antibody SGCA_HUMAN antibody
• Abbreviation: Alpha-SG, 50DAG, SGCA
• CAS Number: 9000-83-3
• Swiss Prot: Q16586 Human, P82350 Mouse, Q5SWB2 Rat
• Cellular Locus: Sarcolemma, cytoskeleton.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within Human alpha sarcoglycan aa 338-387 / 387.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IP, IHC-P, IF-Tissue
• Positive Control: Mouse heart tissue lysate, Mouse skeletal muscle tissue lysate, Rat heart tissue lysate, Rat skeletal muscle tissue lysate, mouse heart tissue lysate, human skeletal muscle tissue lysate, human skeletal muscle tissue, mouse skeletal muscle tissue, rat skeletal muscle tissue, mouse heart tissue, rat heart tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000 ;IHC-P: 1:200-1:1,000 ;IP: 1-2μg/sample ;IF-Tissue: 1:200
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 43 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes