58K Golgi protein Recombinant Rabbit Monoclonal Antibody [JF099-5]

58K Golgi protein Recombinant Rabbit Monoclonal Antibody [JF099-5]

• Description: 58K protein antibodies are excellent for use as markers for the Golgi complex. The 58K protein has been identified as being FTCD, a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Defects in FTCD are the cause of glutamate formiminotransferase deficiency [also known as formiminoglutamicaciduria (FIGLU-uria)], an autosomal recessive disorder. Features of a severe phenotype include elevated levels of formiminoglutamate (FIGLU) in the urine in response to histidine administration, megaloblastic anemia and mental retardation. Features of a mild phenotype include high urinary excretion of FIGLU in the absence of histidine administration, mild developmental delay and no hematological abnormalities.
• Product Name Alternative: Formimidoyltetrahydrofolate cyclodeaminase antibody Formimidoyltransferase cyclodeaminase antibody Formiminotetrahydrofolate cyclodeaminase antibody Formiminotransferase cyclodeaminase antibody Formiminotransferase-cyclodeaminase antibody FTCD antibody FTCD_HUMAN antibody Glutamate formiminotransferase antibody Glutamate formyltransferase antibody LCHC 1 antibody LCHC1 antibody
• Abbreviation: FTCD, LCHC1, FTCD
• CAS Number: 9000-83-3
• Swiss Prot: O95954 Human
• Cellular Locus: Cytoplasm, Golgi apparatus.
• Host: Rabbit
• Species Reactivity: Human
• Immunogen: Synthetic peptide within Human 58K Golgi protein aa 51-100 / 541.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IHC-P, FC
• Positive Control: Human liver tissue, human kidney tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500-1:1,000;FC: 1:50-1:100;IHC-P: 1:50-1:200
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: 59 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes