Kv1.1 potassium channel Recombinant Rabbit Monoclonal Antibody [SN66-06]

Kv1.1 potassium channel Recombinant Rabbit Monoclonal Antibody [SN66-06]

• Description: Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles, and other excitable cells. The KV gene family encodes more than 30 genes that comprise the subunits of the K⁺ channels, and they vary in their gating and permeation properties, subcellular distribution, and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming -subunits (KVα), which include the KV1, KV2, KV3, and KV4 proteins, and accessory or KVβ subunits that modify the gating properties of the coexpressed KVα subunits. Differences exist in the patterns of trafficking, biosynthetic processing and surface expression of the major KV1 subunits (KV1.1, KV1.2, KV1.4, KV1.5 and KV1.6) expressed in rat and human brain, suggesting that the individual protein subunits are highly regulated to control for the assembly and formation of functional neuronal channels.
• Product Name Alternative: AEMK antibody EA1 antibody Episodic ataxia with myokymia antibody HBK1 antibody HUK1 antibody Kca1 1 antibody Kcna1 antibody KCNA1_HUMAN antibody Kcpvd antibody KV1.1 antibody MBK1 antibody mceph antibody MGC124402 antibody MGC126782 antibody MGC138385 antibody MK1 antibody MK1, mouse, homolog of KV1.1 antibody Potassium channel protein 1 antibody Potassium voltage gated channel shaker related subfamily member 1 antibody Potassium voltage gated channel subfamily A member 1 antibody Potassium voltage gated channel, shaker related subfamily, member 1 (episodic ataxia with myokymia) antibody Potassium voltage-gated channel subfamily A member 1 antibody RBK1 antibody RCK1 antibody Shak antibody Shaker related subfamily member 1 antibody Voltage gated potassium channel subunit Kv1.1 antibody Voltage-gated K (+) channel HuKI antibody Voltage-gated potassium channel HBK1 antibody Voltage-gated potassium channel subunit Kv1.1 antibody
• Abbreviation: KCNA1
• CAS Number: 9000-83-3
• Swiss Prot: Q09470 Human, P16388 Mouse, P10499 Rat
• Cellular Locus: Cell membrane, Membrane, Cytoplasmic vesicle, Perikaryon, Endoplasmic reticulum.
• Host: Rabbit
• Species Reactivity: Human, Rat, Mouse
• Immunogen: Synthetic peptide within Human KCNA1 aa 491-440 / 495.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IHC-P, IP
• Positive Control: Human brain tissue lysates, rat brain tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:2,000-1:5,000 ;IHC-P: 1:50-1:200 ;IP: Use at an assay dependent concentration.
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 56 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes