M-CSF Recombinant Rabbit Monoclonal Antibody [SU0413]

M-CSF Recombinant Rabbit Monoclonal Antibody [SU0413]

• Description: The macrophage colony-stimulating factor (M-CSF), also designated CSF-1, was originally discovered in serum, urine and other biological fluids as a factor that can stimulate the formation of macrophage colonies from bone marrow hematopoietic progenitor cells. M-CSF is a homodimeric cytokine that is produced by fibroblasts, epithelial cells, bone marrow stromal cells, osteoblasts, keratinocytes, macrophages, T cells and B cells. M-CSF is a glycoprotein required for the proliferation and differentiation of mononuclear phagocytes, including osteoclasts. M-CSF has also been identified as an important mediator of the inflammatory response and can regulate the release of proinflammatory cytokines from macrophages. M-CSF exerts its pleiotropic effects by binding to a single type of high affinity cell surface receptor that is encoded by the c-Fms proto-oncogene.
• Product Name Alternative: Colony stimulating factor 1 (macrophage) antibody Colony stimulating factor 1 antibody Colony stimulating factor macrophage specific antibody CSF 1 antibody CSF-1 antibody CSF1 antibody CSF1_HUMAN antibody Csfm antibody Lanimostim antibody M CSF antibody M-CSF antibody Macrophage Colony Stimulating Factor 1 antibody Macrophage colony stimulating factor antibody MCSF antibody MGC31930 antibody Processed macrophage colony-stimulating factor 1 antibody
• Abbreviation: CSF-1, M-CSF, MCSF, CSF1
• CAS Number: 9000-83-3
• Swiss Prot: P09603 Human, P07141 Mouse
• Cellular Locus: Membrane, Secreted, extracellular space, nuclear body.
• Host: Rabbit
• Species Reactivity: Human, Mouse
• Immunogen: Synthetic peptide within Human M-CSF aa 56-105 / 554.
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IHC-P, IF-Cell, IP
• Positive Control: Jurkat cell lysates, mouse colon tissue lysates, A431, HepG2, Hela, mouse colon tissue, human lung tissue, human liver tissue, human kidney tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:500-1:1,000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:50-1:2,000 ;IP: Use at an assay dependent concentration.
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 60 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: Yes