CD28 Rabbit Polyclonal Antibody
CAT:
992-ER2001-42
Size:
100 µL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
CD28 Rabbit Polyclonal Antibody
- Description: CD28 (Cluster of Differentiation 28) is one of the proteins expressed on T cells that provide co-stimulatory signals required for T cell activation and survival. T cell stimulation through CD28 in addition to the T-cell receptor (TCR) can provide a potent signal for the production of various interleukins (IL-6 in particular). CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2) proteins. When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen-presenting cells (APCs). The CD86 expression on antigen-presenting cells is constitutive (expression is independent of environmental factors). CD28 is the only B7 receptor constitutively expressed on naive T cells. Association of the TCR of a naive T cell with MHC:antigen complex without CD28:B7 interaction results in a T cell that is anergic.
- Product Name Alternative: CD 28 antibody CD28 antibody CD28 antigen antibody CD28 molecule antibody CD28_HUMAN antibody MGC138290 antibody T cell antigen CD28 antibody T cell specific surface glycoprotein antibody T cell specific surface glycoprotein CD28 antibody T-cell-specific surfac
- Abbreviation: TP44,T-cell-specific surface glycoprotein CD28
- CAS Number: 9007-83-4
- Swiss Prot: P10747 Human, P31041 Mouse, P31042 Rat
- Cellular Locus: Membrane.
- Host: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Immunogen: Synthetic peptide within human CD28 aa 170-220.
- Isotype: IgG
- Conjugation: Non-conjugated
- Type: Rabbit polyclonal Antibody
- Applications: WB, IHC-P, FC
- Positive Control: Mouse spleen tissue lysate, U937 cell lysate, rat spleen tissue, human tonsils tissue, human spleen tissue, mouse spleen tissue, Jurkat.
- Concentration: 1 mg/mL
- Dilution: WB: 1:500-1:1,000;IHC-P: 1:50-1:200;FC: 1:100-1:500
- Purity: Immunogen affinity purified.
- Form: Liquid
- Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
- Molecular Weight: Predicted band size: 25 kDa.
- Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
- Recombinant Antibody: No