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CD21 Rabbit Polyclonal Antibody

CAT: 0992-ER1706-56Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER1706-56Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CD21 (also known as complement receptor (CR) type 2) is a type I integral membrane glycoprotein that serves as a receptor for the C3d complement fragment and for the Epstein-Barr virus. It plays a role in B cell activation and proliferation and undergoes phosphorylation after B cell activation with phorbol esters. CD21 is expressed on mature B cells, follicular dendritic cells, pharyngeal and cervical epithelial cells and a subset of thymocytes. The adaptive immune response is tightly regulated to limit responding cells in an antigen-specific manner. On B cells, co-receptors CD21/CD19 modulate the strength of B cell Ag receptor (BCR) signals, thereby influencing cell fate. CD21 is normally expressed during the immature and mature stages of B cell development. In association with CD19, CR21 plays an important role in enhancing mature B cell responses to foreign antigens.
CAS Number
9007-83-4
Product Name Alternative
C3DR antibody CD 21 antibody CD21 antibody Complement C3d receptor 2 antibody Complement C3d receptor antibody Complement component (3d/Epstein Barr virus) receptor 2 antibody Complement receptor type 2 antibody CR antibody Cr2 antibody CR2_HUMAN antibody CVID7 antibody EBV receptor antibody EBV-R antibody Epstein Barr virus receptor antibody Epstein-Barr virus receptor antibody EVBR antibody SLEB9 antibody
Abbreviation
Cr2, EBV receptor, CR2, C3DR
Swiss Prot
P20023 Human
Cellular Locus
Membrane.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within Human CD21 aa 984-1,033 / 1,033.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
IF-Cell, IHC-P, FC
Positive Control
LOVO, SH-SY5Y, human tonsil tissue, human colon cancer tissue.
Concentration
1 mg/mL
Dilution
IHC-P: 1:50-1:200;IF-Cell: 1:50-1:200;FC: 1:50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 113 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

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