FH Rabbit Polyclonal Antibody

• Description:

  The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.

• Product Name Alternative:

  FH antibody Fumarase antibody Fumarate hydratase antibody Fumarate hydratase mitochondrial antibody Fumarate hydratase, mitochondrial antibody FUMH_HUMAN antibody HLRCC antibody LRCC antibody MCL antibody MCUL 1 antibody MCUL1 antibody MS709 antibody Multiple hereditary cutaneous leiomyomata antibody

• Abbreviation:

  FH

• Swiss Prot:

  P07954 Human, P97807 Mouse, P14408 Rat

• Cellular Locus:

  Mitochondrion, cytosol, nucleus, chromosome.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein within Human FH aa 83-267 / 510.

• Isotype:

  IgG

• Conjugation:

  Non-conjugated

• Type:

  Rabbit polyclonal Antibody

• Applications:

  WB, IF-Cell, IHC-P, FC

• Positive Control:

  K562 cell lysates, LOVO, SiHa, rat testis tissue, human liver tissue, human liver carcinoma tissue, mouse colon tissue, HCT116, LO2 cell lysate, mouse liver tissue lysate, rat liver tissue lysate.

• Concentration:

  1 mg/mL

• Dilution:

  WB:1:500-1:1,000 ;IF-Cell:1:50-1:100 ;IHC-P:1:50-1:200 ;FC:1:50-1:100

• Purity:

  Immunogen affinity purified.

• Form:

  Liquid

• Buffer:

  1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size: 55 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  No

• CAS Number:

  9007-83-4