Glutathione Reductase Rabbit Polyclonal Antibody

• Description:

  Glutathione plays a key role in maintaining proper function and preventing oxidative stress in human cells. It can act as a scavenger for hydroxyl radicals, singlet oxygen, and various electrophiles. Reduced glutathione reduces the oxidized form of the enzyme glutathione peroxidase, which in turn reduces hydrogen peroxide (H2O2), a dangerously reactive species within the cell. In addition, it plays a key role in the metabolism and clearance of xenobiotics, acts as a cofactor in certain detoxifying enzymes, participates in transport, and regenerates antioxidants such and Vitamins E and C to their reactive forms. The ratio of GSSG/GSH present in the cell is a key factor in properly maintaining the oxidative balance of the cell, that is, it is critical that the cell maintains high levels of the reduced glutathione and a low level of the oxidized Glutathione disulfide. This narrow balance is maintained by glutathione reductase, which catalyzes the reduction of GSSG to GSH.

• Product Name Alternative:

  GLR1 antibody GLUR antibody Glutathione reductase antibody Glutathione reductase mitochondrial antibody Glutathione reductase, mitochondrial antibody GR antibody Gr1 antibody GRase antibody GRD 1 antibody GRD1 antibody GSHR_HUMAN antibody GSR antibody MGC78522 antibody

• Abbreviation:

  GR, GRase, GSR, GLUR, GRD1

• Swiss Prot:

  P00390 Human, P70619 Rat

• Cellular Locus:

  Cytoplasm. Mitochondrion.

• Host:

  Rabbit

• Species Reactivity:

  Human, Rat

• Immunogen:

  Recombinant protein within Human GLUR aa 273-446 / 522.

• Isotype:

  IgG

• Conjugation:

  Non-conjugated

• Type:

  Rabbit polyclonal Antibody

• Applications:

  WB, IF-Cell, IHC-P, FC

• Positive Control:

  A549, rat liver tissue, rat epididymis tissue, human liver tissue, human thyroid gland tissue.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:1,000-1:2,000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100

• Purity:

  Immunogen affinity purified.

• Form:

  Liquid

• Buffer:

  1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size: 56 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  No

• CAS Number:

  9007-83-4