GOLPH3 Rabbit Polyclonal Antibody

• Description:

  GOLPH3 (golgi phosphoprotein 3), also known as GOPP1, GPP34 or MIDAS, is a 298 amino acid protein that localizes to both the cytoplasm and the Golgi stack membrane where it is thought to play a regulatory role in protein trafficking within the Golgi. GOLPH3 is subject to post-translational phosphorylation and is encoded by a gene which maps to human chromosome 5. Chromosome 5 contains 181 million base pairs and comprises nearly 6% of the human genome. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5-associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

• Product Name Alternative:

  Coat protein antibody Coat protein GPP34 antibody FLJ90675 antibody Golgi associated protein antibody Golgi peripheral membrane protein 1, 34 kDa antibody Golgi phosphoprotein 3 (coat protein) antibody Golgi phosphoprotein 3 antibody Golgi protein antibody GOLP3_HUMAN antibody Golph3 antibody GOPP1 antibody GPP34 antibody MIDAS antibody Mitochondrial DNA absence factor antibody

• Abbreviation:

  MIDAS, GOLPH3, GPP34

• Swiss Prot:

  Q9H4A6 Human, Q9CRA5 Mouse, Q9ERE4 Rat

• Cellular Locus:

  Cell membrane. Endosome. Cytoplasm.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein within C-terminal human GOLPH3.

• Isotype:

  IgG

• Conjugation:

  Non-conjugated

• Type:

  Rabbit polyclonal Antibody

• Applications:

  WB, IF-Cell, IHC-P, FC

• Positive Control:

  Hela, HepG2, SK-Br-3, rat epididymis tissue, human stomach cancer tissue, mouse stomach tissue.

• Concentration:

  1 mg/mL

• Dilution:

  IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200;FC: 1:50-1:100;WB: 1:500

• Purity:

  Protein A affinity purified.

• Form:

  Liquid

• Buffer:

  1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  34 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

• Recombinant Antibody:

  No

• CAS Number:

  9007-83-4