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NaV1.8 Rabbit Polyclonal Antibody

CAT: 0992-ER1706-30Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-ER1706-30Size:100 µL
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Description
Tetrodotoxin-resistant channel that mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. Plays a role in neuropathic pain mechanisms.
CAS Number
9007-83-4
Product Name Alternative
hPN3 antibody mPN3 antibody Peripheral nerve sodium channel 3 antibody Pn3 (gene name) antibody PN3 antibody SCN10A antibody SCNAA_HUMAN antibody Sensory neuron sodium channel antibody Sns (gene name) antibody SNS antibody Sodium channel protein type 10 subunit alpha antibody Sodium channel protein type X alpha subunit antibody Sodium channel protein type X subunit alpha antibody Voltage-gated sodium channel alpha subunit Nav1.8 antibody Voltage-gated sodium channel subunit alpha Nav1.8 antibody
Abbreviation
PN3, Scn10a, Sns
Swiss Prot
Q6QIY3 Mouse, Q62968 Rat
Cellular Locus
Plasma membrane.
Host
Rabbit
Species Reactivity
Mouse, Rat
Immunogen
Synthetic peptide within rat NaV18 aa 1,907-1,956 / 1,956.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P
Positive Control
Rat spinal cord lysates, mouse brain tissue, mouse brain tissue lysates.
Concentration
1 mg/mL
Dilution
WB: 1:100-1:1,000 ;IHC-P: 1:50-1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 220 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

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