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CD105 Rabbit Polyclonal Antibody

CAT: 0992-0902-1Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0992-0902-1Size:100 µL
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Description
Endoglin is a type I membrane glycoprotein located on cell surfaces and is part of the TGF beta receptor complex. The protein consists of a homodimer of 180 kDA with disulfide links. It has been found on endothelial cells, activated macrophages, fibroblasts, and smooth muscle cells. Endoglin has been found to be part of the TGF-beta1 receptor complex. It thus may be involved in the binding of TGF-beta1, TGF-beta3, activin-A, BMP-2, and BMP-7. In humans endoglin may be involved in the autosomal dominant disorder known as hereditary hemorrhagic telangiectasia type 1. This condition leads to frequent nose bleeds, telangiectases on skin and mucosa and may cause arteriovenous malformations in different organs including brain, lung, and liver.
CAS Number
9007-83-4
Product Name Alternative
AI528660 antibody AI662476 antibody CD 105 antibody CD105 antibody CD105 antigen antibody EGLN_HUMAN antibody END antibody Endoglin antibody Eng antibody FLJ41744 antibody HHT1 antibody ORW antibody ORW1 antibody Osler Rendu Weber syndrome 1 antibody RP11 228B15.2 antibody S-endoglin antibody SN6 antibody
Abbreviation
CD105
Swiss Prot
Q63961 Mouse
Cellular Locus
Cell membrane
Host
Rabbit
Species Reactivity
Mouse
Immunogen
Synthetic peptide within mouse CD105 aa 16-65 / 653.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
CD3
Concentration
1 mg/mL
Dilution
WB: 1:500
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
74kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

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