Recombinant Human CCL14, biotinylated

Recombinant Human CCL14, biotinylated

• Description: Recombinant human CCL14
• Product Name Alternative: rHuCCL14-biotin, HCC-1
• CAS Number: 9000-83-3
• Gene Name: CCL14
• UniProt: Q16627
• Cellular Locus: Secreted.
• Reactivity: Human
• Target Antigen: C-C motif chemokine 14
• Target: CCL14ylated
• Type: Protein
• Applications: Migration assay
• Dilution: Centrifuge tube prior to resuspending. Recommended at 100ug/ml in sterile distilled water.
• Form: Lyophilized
• Function: Has weak activities on human monocytes and acts via receptors that also rPubMed:11085751}.
• Additionnal Information: Endotoxin Level: <0.01 EU per 1ug of protein by LAL method.Migration Assay in cells expressing CCR1.
• Storage Conditions: 12 months from date of receipt, -20°C to -70°C, as supplied. 1 month,- 20°C to -70°C, under sterile conditions after reconstitution. Best if used immediately after reconstitution. Avoid multiple freeze-thaw cycles.
• Specificity: CCL14ylated
• Target Background: CCL14, also known as Hemofiltrate CC Chemokine-1 (HCC-1) is a small cytokine (~8kDa) that is constitutively expressed in multiple tissues. Upon processing of the N-terminal residues of full- length HCC-1 by the uPA-plasmin system, the active form of HCC-1 is a strong agonist for CCR1, CCR5, and, to a lesser extent, CCR3. CCL14 causes chemotaxis of different types of leukocytes, and its active form is a potent inhibitor of HIV entry.