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GLUT4 antibody

CAT: 0710-FNab10684Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab10684Size:100 µg
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Background
This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM) .
Synonyms
Solute carrier family 2, facilitated glucose transporter member 4|Glucose transporter type 4, insulin-responsive (GLUT-4) |SLC2A4|GLUT4
Gene ID
6517
UniProt
P14672
Host
Mouse
Reactivity
Human, Mouse, Rat
Immunogen
Solute carrier family 2 (facilitated glucose transporter), member 4
Target
GLUT4
Clonality
Monoclonal
Isotype
IgG2b
Applications
ELISA, WB, IHC, IF
Field of Research
Metabolism
Purification
Protein A+G purification
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
55 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
4G1
Tested Applications
ELISA, WB, IHC, IF
Immunogen Sequence
Peptide

UniProtKB · P14672

Solute carrier family 2, facilitated glucose transporter member 4

GLUT4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P14672
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SLC2A4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q05BQ3, Q14CX2
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneCytoplasmMembrane

Disease

Diabetes mellitusDisease variant

PTM

GlycoproteinLipoproteinPalmitatePhosphoproteinUbl conjugation

Biological process

Sugar transportTransport

Domain

TransmembraneTransmembrane helix

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