MMP-9 Recombinant Rabbit Monoclonal Antibody [PSH06-33]

MMP-9 Recombinant Rabbit Monoclonal Antibody [PSH06-33]

• Description: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, angiogenesis, bone development, wound healing, cell migration, learning and memory, as well as in pathological processes, such as arthritis, intracerebral hemorrhage, and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens and other extracellular matrix proteins. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. Thrombospondins, intervertebral disc proteins, regulate interaction with matrix metalloproteinases (MMPs) 2 and 9, which are key effectors of ECM remodeling.
• Product Name Alternative: 82 kDa matrix metalloproteinase-9 antibody 92 kDa gelatinase antibody 92 kDa type IV collagenase antibody CLG 4B antibody CLG4B antibody Collagenase Type 4 beta antibody Collagenase type IV 92 KD antibody EC 3.4.24.35 antibody Gelatinase 92 KD antibody Gelatinase B antibody Gelatinase beta antibody GelatinaseB antibody GELB antibody Macrophage gelatinase antibody MANDP2 antibody Matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) antibody Matrix Metalloproteinase 9 antibody MMP 9 antibody MMP-9 antibody MMP9 antibody MMP9_HUMAN antibody Type V collagenase antibody
• Abbreviation: MMP9, CLG4B
• CAS Number: 9000-83-3
• Swiss Prot: P14780 Human
• Cellular Locus: Secreted, extracellular space, extracellular matrix.
• Host: Rabbit
• Species Reactivity: Human
• Immunogen: Recombinant protein within human MMP-9 aa 1-707.
• Isotype: IgG
• Clone: PSH06-33
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IHC-P
• Positive Control: U-2 OS treated with 200nM TPA for 24 hours cell lysate, human spleen tissue, human tonsil tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:2,000 ;IHC-P: 1:1,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 78 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes