Peptide E

• Description :

  Peptide E is a potent kappa opiate receptor agonist. Peptide E has opiate receptor binding activity with IC50 value of 0.39 μM. Peptide E can be used for the research of central nervous system[1][2].

• UNSPSC :

  12352209

• Target :

  Opioid Receptor

• Type :

  Peptides

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/peptide-e.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(NCC(NCC(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCSC)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(NCC(N[C@@H](CCCNC(N)=N)C(N2[C@@H](CCC2)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC3=CNC4=CC=CC=C34)C(N[C@@H](CC5=CNC6=CC=CC=C56)C(N[C@@H](CCSC)C(N[C@@H](CC(O)=O)C(N[C@@H](CC7=CC=C(C=C7)O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC8=CC=C(C=C8)O)C(NCC(NCC(N[C@@H](CC9=CC=CC=C9)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC%10=CC=C(C=C%10)O)N

• Molecular Formula :

  C147H207N41O34S2

• Molecular Weight :

  3156.61

• References & Citations :

  [1]E P Heimer, et al. Synthesis of adrenal peptide E and some of its biological activities. Arch Biochem Biophys. 1983 Sep;225 (2) :518-24.|[2] R Quirion, et al. Peptide E and other proenkephalin-derived peptides are potent kappa opiate receptor agonists. Peptides. 1983 Jul-Aug;4 (4) :445-9.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported

• CAS Number :

  [78355-50-7]