α-Glucosidase-IN-22

α-Glucosidase-IN-22

• CAS Number: 2870693-28-8
• UNSPSC Description: α-Glucosidase-IN-22 (compound 7i), a benzimidazole, is a potent α-glucosidase inhibitor with an IC50 of 0.64 μM. α-Glucosidase-IN-22 is a potent anti-diabetic agent and has the potential for type 2 diabetes mellitus (T2DM) research[1].
• Target Antigen: Glycosidase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-sugar/lipid metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/α-glucosidase-in-22.html
• Solubility: DMSO : 125 mg/mL (ultrasonic)
• Smiles: S=C1NC2=CC=C(C=C2N1)/N=C/C3=CC=C(C=C3O)O
• Molecular Weight: 285.32
• References & Citations: [1]Sardar Ali, et al. Novel 5-(Arylideneamino)-1 H-Benzo[ d]imidazole-2-thiols as Potent Anti-Diabetic Agents: Synthesis, In Vitro α-Glucosidase Inhibition, and Molecular Docking Studies. ACS Omega. 2022 Nov 23;7(48):43468-43479.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported