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BQ7876

CAT: 0804-HY-P10743Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P10743Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BQ7876 is a probe targeting prostate-specific membrane antigen (PSMA) that contains a DOTA chelator. BQ7876, after being radiolabeled with radionuclide (177Lu), functions in both radionuclide imaging and tumor cell destruction by specifically binding to PSMA. BQ7876 shows potential for research in the field of metastatic castration-resistant prostate cancer (mCRPC) [1]. BQ7876 can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs) .
UNSPSC
12352209
Target
PSMA; Radionuclide-Drug Conjugates (RDCs)
Type
Peptides
Related Pathways
Antibody-drug Conjugate/ADC Related; Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bq7876.html
Smiles
O=C(CN1CCN(CCN(CCN(CC1)CC(O)=O)CC(O)=O)CC(NCCCC[C@H](NC(C)=O)C(NCCCCCCCC(N[C@H](C(N[C@H](C(NCCCC[C@@H](C(O)=O)NC(N[C@H](C(O)=O)CCC(O)=O)=O)=O)CC2=CC3=C(C=C2)C=CC=C3)=O)CC4=CC=C(O)C=C4)=O)=O)=O)O
Molecular Formula
C66H96N12O20
Molecular Weight
1377.54
References & Citations
[1]Abouzayed A, et al. 177Lu-labeled PSMA targeting therapeutic with optimized linker for treatment of disseminated prostate cancer; evaluation of biodistribution and dosimetry. Front Oncol. 2023 Sep 27;13:1221103.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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