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BQ7859

CAT: 0804-HY-P10744Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P10744Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BQ7859 is a probe targeting PSMA that contains a NOTA chelator and demonstrates excellent imaging performance. BQ7859 can be labeled with various radionuclides, such as 68Ga, 18F, 55Co, and 111In. In a mouse prostate cancer xenograft model, BQ7859 (labeled with 111In) efficiently accumulates in tumor regions in a PSMA-dependent manner and provides high-contrast tumor imaging. BQ7859 shows potential for research in prostate cancer imaging, particularly in positron emission tomography (PET) and single-photon emission computed tomography (SPECT) [1]. BQ7859 can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs) .
UNSPSC
12352209
Target
PSMA; Radionuclide-Drug Conjugates (RDCs)
Type
Peptides
Related Pathways
Antibody-drug Conjugate/ADC Related; Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bq7859.html
Smiles
O=C(CN1CCN(CCN(CC1)CC(O)=O)CC(NCCCC[C@H](NC(C)=O)C(NCCCCCCCC(N[C@H](C(N[C@H](C(NCCCC[C@@H](C(O)=O)NC(N[C@H](C(O)=O)CCC(O)=O)=O)=O)CC2=CC3=C(C=C2)C=CC=C3)=O)CC4=CC=C(O)C=C4)=O)=O)=O)O
Molecular Formula
C62H89N11O18
Molecular Weight
1276.43
References & Citations
[1]Abouzayed A, et al. 177Lu-labeled PSMA targeting therapeutic with optimized linker for treatment of disseminated prostate cancer; evaluation of biodistribution and dosimetry. Front Oncol. 2023 Sep 27;13:1221103.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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