Products for Research Use Only
RegisterLogin

Indacaterol (acetate)

CAT: 0804-HY-14299DSize: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-14299DSize:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Indacaterol acetate is an orally active ultra-long-acting β2 adrenergic receptor (ADRB2) agonist. Indacaterol acetate inhibits NF-κB activity in a β-arrestin2-dependent manner, preventing further lung damage and improving lung function in COPD (chronic obstructive pulmonary disorder) . Indacaterol acetate can also be used in cardiovascular disease research[1][2].
CAS Number
1000160-96-2
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Endocrinology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/indacaterol-acetate.html
Smiles
OC1=CC=C([C@@H](O)CNC2CC(C=C(CC)C(CC)=C3)=C3C2)C4=C1NC(C=C4)=O.CC(O)=O
Molecular Formula
C26H32N2O5
Molecular Weight
452.54
References & Citations
[1]Lee SU, et al. Indacaterol inhibits tumor cell invasiveness and MMP-9 expression by suppressing IKK/NF-κB activation. Mol Cells. 2014 Aug;37 (8) :585-91. |[2]Calzetta L, et al. Effects of the new ultra-long-acting β2-AR agonist indacaterol in chronic treatment alone or in combination with the β1-AR blocker metoprolol on cardiac remodelling. 2015.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched

Chemical Information

Indacaterol Acetate
CAS Number1000160-96-2
PubChem CID24178422
IUPAC Nameacetic acid;5-[(1R)-2-[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy-1H-quinolin-2-one
Molecular FormulaC26H32N2O5
Molecular Weight452.5
Topological Polar Surface Area119
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Heavy Atom Count33
Formal Charge0
Complexity620
SMILES
CCC1=C(C=C2CC(CC2=C1)NC[C@@H](C3=C4C=CC(=O)NC4=C(C=C3)O)O)CC.CC(=O)O
InChI
InChI=1S/C24H28N2O3.C2H4O2/c1-3-14-9-16-11-18(12-17(16)10-15(14)4-2)25-13-22(28)19-5-7-21(27)24-20(19)6-8-23(29)26-24;1-2(3)4/h5-10,18,22,25,27-28H,3-4,11-13H2,1-2H3,(H,26,29);1H3,(H,3,4)/t22-;/m0./s1
InChIKey
HZHXFIDENGBQFQ-FTBISJDPSA-N
Chemical Structure
2D Structure
2D structure of Indacaterol Acetate
CAS: 1000160-96-2
CID: 24178422
Formula: C26H32N2O5
MW: 452.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight452.5
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Exact Mass452.23112213
Monoisotopic Mass452.23112213
Topological Polar Surface Area119 Ų
Heavy Atom Count33
Formal Charge0
Complexity620
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-14299-01Indacaterol
HY-14299CIndacaterol (xinafoate)
HY-14299R-01Indacaterol (Standard)
HY-14299SIndacaterol-d3
HY-14299A-01Indacaterol (maleate)
HY-14299B(S) -Indacaterol
HY-14299AR-01Indacaterol (maleate) (Standard)
HY-166875SApramycin acetate-d7 (acetate)
HY-134716Methyl acetate-PEG1-methyl acetate
HY-W127616-01β-Sitosterol acetate, 40% (contains Campesterol acetate)

Alternative Products

CatalogName
MBS5814197Indacaterol acetate
452287-01Indacaterol
WHC35419Hydroxy indacaterol
452288-01Indacaterol Impurity A

Popular Products