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Indacaterol-d3

CAT: 0804-HY-14299SSize: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-14299SSize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Indacaterol-d3 is deuterium labeled Indacaterol.
CAS Number
2699828-16-3
UNSPSC
12352005
Hazard Statement
H302+H312+H332-H315-H319
Target
Adrenergic Receptor; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Neurological Disease; Endocrinology
Solubility
10 mM in DMSO
Smiles
CCC(C=C(C1)C(CC1NC[C@@H](C2=C3C(NC(C=C3)=O)=C(C=C2)O)O)=C4)=C4CC([2H])([2H])[2H]
Molecular Formula
C24H25D3N2O3
Molecular Weight
395.51
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Battram, C., et al., In vitro and in vivo pharmacological characterization of 5-[ (R) -2- (5,6-diethyl-indan-2-ylamino) -1-hydroxy-ethyl]-8-hydroxy-1H-quinolin-2-o ne (indacaterol), a novel inhaled beta (2) adrenoceptor agonist with a 24-h duration of action. J Pharmacol Exp Ther, 2006. 317 (2) : p. 762-70.|[3]Sturton, R.G., et al., Pharmacological characterization of indacaterol, a novel once daily inhaled 2 adrenoceptor agonist, on small airways in human and rat precision-cut lung slices. J Pharmacol Exp Ther, 2008. 324 (1) : p. 270-5.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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