Influenza A [Darwin/6/2021] Neuraminidase (NA) Protein, His Tag (SPR verified)

• Background:

  Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Neuraminidase, on the other hand, cleaves the HA-sialic acid bondage from the newly formed virions and the host cell receptors during budding. Neuraminidase thus is described as a receptor-destroying enzyme which facilitates virus release and efficient spread of the progeny virus from cell to cell.

• Description:

  Influenza A [Darwin/6/2021] Neuraminidase (NA) Protein, His Tag (NEE-V5247) is expressed from human 293 cells (HEK293) . It contains AA Thr 34 - Ile 469 (Accession # EPI_ISL_3534319, GISAID) .

• Specifications:

  This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 56.5 kDa. The protein migrates as 60-80 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

• Accession Number:

  EPI_ISL_3534319

• Expression Region:

  Thr 34 - Ile 469

• Host:

  HEK293

• Target:

  Neuraminidase/NA (Influenza Virus)

• Conjugation:

  Unconjugated

• Tag:

  N-10xHis

• Source:

  Influenza

• Stability:

  ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

• Endotoxin:

  1.0 EU per μg

• Purity:

  90%

• Format:

  Powder

• Buffer:

  PBS, pH7.4

• Additives:

  Trehalose

• Molecular Weight:

  56.5 kDa

• Shipping Conditions:

  RT

• Storage Conditions:

  -20°C

• Package Size:

  500ug*2

• Species:

  Influenza