Cynomolgus Coagulation factor IX / F9 Protein, His Tag (active enzyme, MALS verified)

• Background:

  Coagulation Factor IX is also known as F9, FIX, and P19. Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca2+ ions, phospholipids, and factor VIIIa，and plays an important role in the intrinsic blood coagulation cascade. As a key component of the clotting cascade, Factor IX helps form stable blood clots and prevents excessive bleeding.

• Description:

  Cynomolgus Coagulation factor IX, His Tag (FIX-C52H9) is expressed from human 293 cells (HEK293) . It contains AA Thr 29 - Thr 461 (Accession # G7Q1U2-1) .

• Specifications:

  This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 50.6 kDa. The protein migrates as 61-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

• Accession Number:

  G7Q1U2-1

• Expression Region:

  Thr 29 - Thr 461

• Host:

  HEK293

• Target:

  Coagulation factor IX

• Conjugation:

  Unconjugated

• Tag:

  C-10xHis

• Source:

  Cynomolgus

• Stability:

  ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

• Endotoxin:

  1.0 EU per μg

• Purity:

  95%

• Format:

  Powder

• Buffer:

  50 mM Tris, 150 mM NaCl, pH7.5

• Additives:

  Trehalose

• Molecular Weight:

  50.6 kDa

• Shipping Conditions:

  RT

• Storage Conditions:

  -20°C

• Package Size:

  20ug*1

• Species:

  Cynomolgus