Cynomolgus Coagulation factor IX / F9 Protein, His Tag (active enzyme, MALS verified)

Cynomolgus Coagulation factor IX / F9 Protein, His Tag (active enzyme, MALS verified)

• Background: Coagulation Factor IX is also known as F9, FIX, and P19. Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca2+ ions, phospholipids, and factor VIIIa，and plays an important role in the intrinsic blood coagulation cascade. As a key component of the clotting cascade, Factor IX helps form stable blood clots and prevents excessive bleeding.
• Description: Cynomolgus Coagulation factor IX, His Tag (FIX-C52H9) is expressed from human 293 cells (HEK293). It contains AA Thr 29 - Thr 461 (Accession # G7Q1U2-1).
• Specifications: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 50.6 kDa. The protein migrates as 61-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expression Region: Thr 29 - Thr 461
• Host: HEK 293
• Target: Coagulation factor IX
• Conjugation: Unconjugated
• Tag: C-10×His
• Source: Cynomolgus
• Stability: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
• Endotoxin: 1.0 EU per μg
• Purity: 95%
• Format: Powder
• Buffer: 50 mM Tris,150 mM NaCl,pH7.5
• Additives: Trehalose
• Molecular Weight: 50.6 kDa
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C