Products for Research Use Only
RegisterLogin

Mouse Complement C3 Protein, His Tag (MALS verified)

CAT: 0716-CO3-M52H4-100ugSize: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0716-CO3-M52H4-100ugSize:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
C3 is the major complement component serum. It is mainly synthesized by macrophages and liver. C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. It is cleaved into two fragments, C3a and C3b. C3a anaphylatoxin is a mediator of local inflammatory process. In chronic inflammation, acts as a chemoattractant for neutrophils. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.
Description
C3 is the major complement component serum. It is mainly synthesized by macrophages and liver. C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. It is cleaved into two fragments, C3a and C3b. C3a anaphylatoxin is a mediator of local inflammatory process. In chronic inflammation, acts as a chemoattractant for neutrophils. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.
Specifications
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 186.1 kDa. The protein migrates as 70 kDa, 100-120 kDa and 160-180 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
P01027-1
Expression Region
Ile 25 - Asn 1663
Host
HEK293
Target
Complement C3
Conjugation
Unconjugated
Tag
C-10xHis
Source
Mouse
Stability
-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
90%
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
186.1 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Host or Source
HEK293
Species
Mouse
Protein ID
P01027-1
Preservative
Trehalose

Related Products

CatalogName
CO3-H52H3-100ugHuman Complement C3 Protein, His Tag (MALS verified)
CO3-C52H5-100ugCynomolgus Complement C3 Protein, His Tag (MALS verified)
CO3-H52H3-1mgHuman Complement C3 Protein, His Tag (MALS verified)
CO3-C52H5-1mgCynomolgus Complement C3 Protein, His Tag (MALS verified)
CO3-H82E8-25ugBiotinylated Human Complement C3 Protein, His, Avitag™ (MALS verified)
CO3-H82E8-200ugBiotinylated Human Complement C3 Protein, His, Avitag™ (MALS verified)
CO5-C52Hx-100ugCynomolgus Complement C5 Protein, His Tag (MALS verified)
CO5-H52Ha-100ugHuman Complement C5 Protein, His Tag (MALS verified)
CO5-H52Ha-1mgHuman Complement C5 Protein, His Tag (MALS verified)
CO5-C52Hx-1mgCynomolgus Complement C5 Protein, His Tag (MALS verified)

Alternative Products

CatalogName
GTR19032273-01Human Complement C1s Protein, His Tag (MALS verified)
GTR18877550-01Cynomolgus Complement C5 Protein, His Tag (MALS verified)
GTR19125786-01Human Complement Factor B Protein, His Tag (MALS & SPR verified)
GTR19125785-01Biotinylated Human Complement Factor B Protein, His, (MALS & SPR verified)
GTR19149904-01Rat CDCP1 Protein, His Tag (MALS verified)
GTR19149804-01Mouse CD98 Protein, His Tag (MALS verified)
GTR19149800-01Mouse CD94 Protein, His Tag (MALS verified)
GTR19125689-01Rat CA125 Protein, His Tag (MALS verified)
GTR19125688-01Rat CD94 Protein, His Tag (MALS verified)
GTR19123458-01Human NKp80 Protein, His Tag (MALS verified)

Popular Products