Biotinylated Cynomolgus / Rhesus macaque BCMA / TNFRSF17 Protein, Fc,Avitag™
CAT:
716-BCA-C82F4-25ug
Size:
25 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Biotinylated Cynomolgus / Rhesus macaque BCMA / TNFRSF17 Protein, Fc,Avitag™
- Background: Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.
- Description: Biotinylated Cynomolgus / Rhesus macaque BCMA, Fc,Avitag (BCA-C82F4) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 53 (Accession # A0A2K5UD97-1). In the region Met 1 - Ala 53, the AA sequence of Cynomolgus and Rhesus macaque BCMA are homologus.
- Specifications: This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 33.9 kDa. The protein migrates as 42-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Expression Region: Met 1 - Ala 53
- Host: HEK 293
- Target: BCMA
- Conjugation: Biotin-labeled
- Tag: C-Fc & C-Avi
- Source: Cynomolgus / Rhesus macaque
- Stability: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
- Endotoxin: 1.0 EU per μg
- Purity: 95%
- Bioactivity: Immobilized Human BAFF, Fc Tag, active trimer (Cat. No. BAF-H5261) at 5 μg/mL (100 μL/well) can bind Biotinylated Cynomolgus / Rhesus macaque BCMA, Fc,Avitag (Cat. No. BCA-C82F4) with a linear range of 0.1-6 ng/mL (QC tested).
- Format: Powder
- Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
- Additives: Trehalose
- Molecular Weight: 33.9 kDa
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C