EZH2-IN-15

EZH2-IN-15

• CAS Number: 2098545-98-1
• UNSPSC Description: EZH2-IN-15 is a EZH2 inhibitor. EZH2-IN-15 has anti-tumor activity, and can be used for research of H3K27me3-dependent tumors[1].
• Target Antigen: Histone Methyltransferase
• Type: Reference compound
• Related Pathways: Epigenetics
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/ezh2-in-15.html
• Solubility: DMSO : 125 mg/mL (ultrasonic)
• Smiles: O=C1NC(C)=CC(C)=C1CNC(C2=C3C=C(CN4CCCCC4)OC3=CC(N(C5CCOCC5)CC)=C2CC)=O
• Molecular Weight: 548.72
• References & Citations: [1]Dale B, et al. Targeting Triple-Negative Breast Cancer by a Novel Proteolysis Targeting Chimera Degrader of Enhancer of Zeste Homolog 2. ACS Pharmacol Transl Sci. 2022 Jun 24;5(7):491-507.
• Shipping Conditions: Room Temperature
• Clinical Information: Phase 3