PI3K/AKT-IN-2

PI3K/AKT-IN-2

• CAS Number: 2684412-41-5
• UNSPSC Description: PI3K/AKT-IN-2 (Compound 12c) is a PI3K and AKT inhibitor. PI3K/AKT-IN-2 blocks the epithelial-mesenchymal transition (EMT) and induces apoptosis. PI3K/AKT-IN-2 inhibits the polymerization of tubulin[1].
• Target Antigen: Akt; Apoptosis; Microtubule/Tubulin; MMP; PI3K
• Type: Reference compound
• Related Pathways: Apoptosis;Cell Cycle/DNA Damage;Cytoskeleton;Metabolic Enzyme/Protease;PI3K/Akt/mTOR
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/pi3k-akt-in-2.html
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O=C(O[C@@H]1[C@]2([H])[C@@](C(OC2)=O)([H])[C@H](C3=CC(OC)=C(OC)C(OC)=C3)C4=C1C=C5OCOC5=C4)/C=C/C(C6=CC=C(Br)C=C6)=O
• Molecular Weight: 651.45
• References & Citations: [1]Sun W, et al. Design, semi-synthesis and bioactivity evaluation of novel podophyllotoxin derivatives as potent anti-tumor agents. Bioorg Chem. 2022 May 26;126:105906.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported