Dipentyl phthalate
CAT:
804-HY-W013816-01
Size:
5 g
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Dipentyl phthalate
- CAS Number: 131-18-0
- UNSPSC Description: Dipentyl phthalate is an endocrine-disrupting phthalate plasticizer. Dipentyl phthalate increases AMPK phosphorylation and decreases AKT1 phosphorylation and SIRT1 levels. Dipentyl phthalate reduces adrenocorticotropic hormone levels. Dipentyl phthalate is a testicular toxicant[1].
- Target Antigen: Akt; AMPK
- Type: Reference compound
- Related Pathways: Epigenetics;PI3K/Akt/mTOR
- Applications: Metabolism-sugar/lipid metabolism
- Field of Research: Metabolic Disease
- Assay Protocol: https://www.medchemexpress.com/dipentyl-phthalate.html
- Purity: 99.42
- Solubility: DMSO : ≥ 100 mg/mL
- Smiles: O=C(OCCCCC)C1=CC=CC=C1C(OCCCCC)=O
- Molecular Weight: 306.402
- References & Citations: [1]Haiqiong Chen, et al. Exposure to dipentyl phthalate in utero disrupts the adrenal cortex function of adult male rats by inhibiting SIRT1/PGC-1α and inducing AMPK phosphorylation. Environ Toxicol. 2023 May;38(5):997-1010.|[2]Bethany R Hannas, et al. Dipentyl phthalate dosing during sexual differentiation disrupts fetal testis function and postnatal development of the male Sprague-Dawley rat with greater relative potency than other phthalates. Toxicol Sci. 2011 Mar;120(1):184-93.
- Shipping Conditions: Room Temperature
- Storage Conditions: Store at room temperature 3 years
- Clinical Information: No Development Reported