CD31 Recombinant Mouse Monoclonal Antibody [7-A1-R]

• Description:

  Cell adhesion molecules are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are thought to play an important role in embryogenesis and development. Neuronal cell adhesion molecule (NCAM) expression is observed in a variety of human tumors including neuroblastomas, rhabdomyosarcomas, Wilms’ tumors, Ewing’s sarcomas and some primitive myeloid malignancies. The intracellular adhesion molecule-1 (ICAM-1), also referred to as CD54, is an integral membrane protein of the immunoglobulin superfamily. PECAM-1 (platelet/endothelial cell adhesion molecule-1), also referred to as CD31, is a glycoprotein expressed on the cell surfaces of monocytes, neutrophils, platelets and a subpopulation of T cells. VCAM-1 (vascular cell adhesion molecule-1) was first identified as an adhesion molecule induced on human endothelial cells by inflammatory cytokines such as IL-1, tumor necrosis factor (TNF) and lipopolysaccharide (LPS). The KALIG gene encodes a nerve cell adhesion molecule (NCAM)-like protein and is deleted in 66% of patients with Kallmann’s syndrome, anosmia with secondary hypogonadism.

• Product Name Alternative:

  Adhesion molecule antibody CD31 antibody CD31 antigen antibody CD31 EndoCAM antibody EndoCAM antibody FLJ34100 antibody FLJ58394 antibody GPIIA antibody GPIIA' antibody PECA1 antibody PECA1_HUMAN antibody Pecam 1 antibody PECAM 1 CD31 EndoCAM antibody PECAM antibody PECAM-1 antibody Pecam1 antibody Platelet and endothelial cell adhesion molecule 1 antibody Platelet endothelial cell adhesion molecule antibody Platelet/endothelial cell adhesion molecule 1 antibody

• Abbreviation:

  PECAM-1

• Swiss Prot:

  P16284 Human

• Cellular Locus:

  Cell junction. Cell membrane. Membrane.

• Host:

  Mouse

• Species Reactivity:

  Human

• Immunogen:

  Synthetic peptide (KLH-coupled) within C-terminal residues of human CD31.

• Isotype:

  IgG1

• Clone:

  7-A1-R

• Conjugation:

  Non-conjugated

• Type:

  Recombinant Mouse monoclonal Antibody

• Applications:

  WB, IF-Cell, IHC-P

• Positive Control:

  THP-1 cell lysate, Jurkat cell lysate, U-937 cell lysate, THP-1, human appendix tissue, human kidney tissue, human liver tissue, human placenta tissue, human stomach cancer tissue.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:2,000 ;IF-Cell: 1:100 ;IHC-P: 1:2,000

• Purity:

  Protein A affinity purified.

• Form:

  Liquid

• Buffer:

  PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size: 83 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  Yes

• CAS Number:

  9000-83-3