Products for Research Use Only
RegisterLogin

Corylifol A

CAT: 0804-HY-N0897-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N0897-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Corylifol A inhibits IL-6-induced STAT3 activation and phosphorylation, with an IC50 of 0.81 μM.
CAS Number
775351-88-7
Product Name Alternative
Corylifol-A; Corylinin
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
STAT; UGT
Type
Natural Products
Related Pathways
JAK/STAT Signaling; Metabolic Enzyme/Protease; Stem Cell/Wnt
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/Corylifol-A.html
Purity
99.90
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C1C(C2=CC=C(O)C(C/C=C(C)/CC/C=C(C)\C)=C2)=COC3=CC(O)=CC=C13
Molecular Formula
C25H26O4
Molecular Weight
390.47
Precautions
H302, H315, H319, H335
References & Citations
[1]Lee SW, et al. Phenolic compounds isolated from Psoralea corylifolia inhibit IL-6-induced STAT3 activation. Planta Med. 2012 Jun;78 (9) :903-6.|[2]Kim DW, et al. Phenolic phytochemical displaying SARS-CoV papain-like protease inhibition from the seeds of Psoralea corylifolia. J Enzyme Inhib Med Chem. 2014 Feb;29 (1) :59-63.|[3]Li YG, et al. Fructus Psoraleae contains natural compounds with potent inhibitory effects towards human carboxylesterase 2. Fitoterapia. 2015 Jan 13;101C:99-106. d
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
STAT3

Chemical Information

Corylifol A

3-{3-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-4-hydroxyphenyl}-7-hydroxychromen-4-one has been reported in Cullen corylifolium and Aspergillus flocculosus with data available.

CAS Number775351-88-7
PubChem CID25056407
IUPAC Name3-[3-[(2E)-3,7-dimethylocta-2,6-dienyl]-4-hydroxyphenyl]-7-hydroxychromen-4-one
Molecular FormulaC25H26O4
Molecular Weight390.5
XLogP6.3
Topological Polar Surface Area66.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count6
Heavy Atom Count29
Formal Charge0
Complexity670
SMILES
CC(=CCC/C(=C/CC1=C(C=CC(=C1)C2=COC3=C(C2=O)C=CC(=C3)O)O)/C)C
InChI
InChI=1S/C25H26O4/c1-16(2)5-4-6-17(3)7-8-19-13-18(9-12-23(19)27)22-15-29-24-14-20(26)10-11-21(24)25(22)28/h5,7,9-15,26-27H,4,6,8H2,1-3H3/b17-7+
InChIKey
ZBHUUXLHDOUMKM-REZTVBANSA-N
Chemical Structure
2D Structure
2D structure of Corylifol A
CAS: 775351-88-7
CID: 25056407
Formula: C25H26O4
MW: 390.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight390.5
XLogP36.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count6
Exact Mass390.18310931
Monoisotopic Mass390.18310931
Topological Polar Surface Area66.8 Ų
Heavy Atom Count29
Formal Charge0
Complexity670
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
B4913-5Corylifol A
T124230-01Corylifol B
A15729-100Corylifol A 100mg
AGB35191-01Corylifol C
A15729-500Corylifol A 500mg
A15729-10Corylifol A 10mg
371307Corylifol A discontinued
A15729-50Corylifol A 50mg
A15729-25Corylifol A 25mg

Popular Products