IE-DAP

• Description :

  IE-DAP is a Nod1 agonist. Nod1 recognition of iE-DAP can activate the NF-κB pathway, leading to an inflammatory cytokine response. iE-DAP can be used for the research of maternal-fetal inflammation and preterm labor[1].

• UNSPSC :

  12352209

• Target :

  NOD-like Receptor (NLR)

• Type :

  Peptides

• Related Pathways :

  Immunology/Inflammation

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Endocrinology

• Assay Protocol :

  https://www.medchemexpress.com/ie-dap.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(O)C(N)CCCC(NC(CC[C@@H](N)C(O)=O)=O)C(O)=O

• Molecular Formula :

  C12H21N3O7

• Molecular Weight :

  319.31

• References & Citations :

  [1]Cardenas I, et al. Nod1 activation by bacterial iE-DAP induces maternal-fetal inflammation and preterm labor. J Immunol. 2011 Jul 15;187 (2) :980-6.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported

• CAS Number :

  [592520-07-5]