Dap-NE

• Description:

  Dap-NE is an intermediate reagent in the synthesis of the ADC toxin Monomethyl auristatin E (HY-15162) [1].

• UNSPSC:

  12352005

• Target:

  ADC Payload

• Type:

  Reference compound

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/dap-ne.html

• Purity:

  99.49

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C(N[C@H](C)[C@@H](O)C1=CC=CC=C1)[C@H](C)[C@@H](OC)[C@H]2NCCC2

• Molecular Formula:

  C18H28N2O3

• Molecular Weight:

  320.43

• References & Citations:

  [1]Xiao Chao, et al. Monomethyl auristatin E single crystal as standard or reference substance and preparation method thereof. China, CN116768966 A. 2023-09-19.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [160800-82-8]