HMGB1-IN-3
CAT:
804-HY-168053
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No

HMGB1-IN-3
- CAS Number: 5195-71-1
- UNSPSC Description: HMGB1-IN-3 (compound E) is a glycyrrhizic acid derivative with strong inhibitory activity against HMGB1 (high mobility group protein 1) and can be used in the study of intracerebral hemorrhage[1].
- Target Antigen: Others
- Type: Reference compound
- Related Pathways: Others
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/hmgb1-in-3.html
- Smiles: C[C@]1(C(OC)=O)CC[C@]([C@@]2([H])C1)(C)CC[C@@](C2=C3)(C)[C@]4(C)CC[C@@]5([H])C(C)(C)C(CC[C@]5(C)[C@@]4([H])C3=O)=O
- Molecular Weight: 482.69
- References & Citations: [1]Machida, et al. "A Glycyrrhizin Derivative with a More Potent Inhibitory Activity against High-Mobility Group Box 1 Efficiently Discovered by Chemical Synthesis Inspired by the Bioconversion Products of an Endophytic Fungus Isolated from Licorice." Journal of Medicinal Chemistry (2024).
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported