(S,R,S)-AHPC-amido-C5-acid

(S,R,S)-AHPC-amido-C5-acid

• CAS Number: 2162120-87-6
• UNSPSC Description: (S,R,S)-AHPC-amido-C5-acid incorporates a VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. (S,R,S)-AHPC-amido-C5-acid can be used to design XY028-133 (HY-129180)[1].
• Target Antigen: E3 Ligase Ligand-Linker Conjugates
• Type: Reference compound
• Related Pathways: PROTAC
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/s-r-s-ahpc-amido-c5-acid.html
• Purity: 99.58
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O=C([C@H]1N(C[C@@H](C1)O)C([C@@H](NC(CCCCCC(O)=O)=O)C(C)(C)C)=O)NCC2=CC=C(C=C2)C3=C(N=CS3)C
• Molecular Weight: 572.72
• References & Citations: [1]Jian Jin, et al. Compositions and methods for treating cdk4/6-mediated cancer. WO2018106870A1.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, sealed storage, away from moisture and light)
• Clinical Information: No Development Reported